Functional Medicine Approach – Take probiotics instead of taking medications for mood regulation?

Have you ever thought about taking the right strains of probiotics for mood enhancer – Using targeted right strains like these will enhance the mood, anxiety, and stress regulation in 1-2 months. It is called Gut-Brain Axis. Adding L. Acidophilus for IBS patients will be helpful.

1. Lactobacillus helveticus R0052 + Bifidobacterium longum R0175

Clinical evidence: This combo has been shown in multiple human studies to: Reduce psychological stress, Lower cortisol, and Improve mood and sleep

Study highlight: A double-blind, placebo-controlled study in British Journal of Nutrition (2011) found that this combo reduced anxiety and depression scores in healthy volunteers.

2. Lactobacillus rhamnosus GG

Mechanism: Influences GABA receptor expression in the brain via the vagus nerve (seen in animal studies).

Effect: May reduce anxiety-like behavior and promote emotional resilience.

Human relevance: Also supports gut barrier integrity, often disrupted in people with mood issues.

3. Lactobacillus plantarum PS128

Neurological impact: Shown to modulate dopamine and serotonin levels in the brain.

Clinical use: Studied in people with autism, anxiety, and ADHD — shown to improve mood and reduce anxiety-like symptoms.